IVF and Menopause: Belmar Pharma Solutions Tells You What You Need to Know

November 2, 2021

By: Belmar Pharmacy

Have you been struggling to get pregnant?

We totally understand your frustration and sadness, because it may feel like the odds are stacked against you.

But look, there is the option of in vitro fertilization (IVF). With this consideration, you may be asking yourself, will it negatively affect your health? Is undergoing fertility treatments the right choice not only for today but for your future self? Let’s dive in and learn more.

What Is IVF?

IVF is a form of assisted reproductive technology (ART) that involves fertilizing an egg in a lab before transferring it to your uterus. A combination of medications and surgical procedures is used to help the sperm fertilize an egg and help that fertilized egg implant successfully in your uterus.

Now that you know what IVF is, let’s talk about some of the known side effects of infertility treatments. While IVF is a common infertility treatment, there’s still not much research on how it affects hormonal health long-term. What we do know is that in some women, it can cause ectopic pregnancy and preeclampsia.

It’s scary to think that a treatment you need to help you become pregnant could also put you at risk. We at Belmar Pharma Solutions don’t want you to worry. To help calm any fears you may be having, we’re going to share with you what you need to know about how IVF affects your hormonal health.

Can IVF Cause Menopause?

The long-term effect of IVF on menopause has not been well-studied. But our own Belmar Pharma Solutions’ Medical Director, Dr. Angela DeRosa, DO, MBA, CPE, found through her research and clinical practice that women are at greater risk for experiencing early menopause.

“Medical professionals often downplay a lot of the risk of IVF and minimize the

experience of women,” Dr. DeRosa said. “Women do have a greater risk

of going through menopause or, at the very least, hormone deficiency after

IVF. It also increases a woman’s risk of ovarian cancer/ovarian

hyperstimulation syndromes.”

What Dr. DeRosa shares is backed up by one recent study, showing a correlation between IVF treatment and urogenital symptoms —  vaginal dryness, itching or discomfort —  found with menopause. But note, IVF has not been proven at this time to have a significant impact on the following menopausal symptoms:

Emotional

  • Anxiety
  • Depressive mood
  • Irritability
  • Mental exhaustion

Physical

  • Coronary discomfort
  • Hot flushes
  • Muscle and joint problems
  • Sleeping problems

While the same study noted above shows that the age of onset for menopause in IVF patients was earlier, the difference between those who had undergone IVF and those who had not isn’t clinically significant and requires more research. Another study found that high doses of ovulation-stimulating drugs like Clomid, a drug used to stimulate ovulation so eggs can be retrieved for IVF, and their repeated use can increase the risk of ovarian cysts, which can lead to ovarian cancer.

While IVF has not been proven to significantly impact mental health, Clomid can impact your mood because it affects how estrogen is perceived in the body.  According to one study, 45% of women experience mood swings while taking the drug, and 41% experience depression. Fortunately, once you complete an IVF cycle, your hormones will return to normal. That is one thing you can look forward to.

Keep in mind that early menopause has many causes outside of fertility treatments, including:

  • Autoimmune conditions
  • Aging
  • Family history
  • Genetic disorders
  • Infection
  • Surgery
  • Toxins

We have shared some of the potential side effects of IVF but as you know everything in medicine has risks and benefits that you should consider with your doctor to determine if infertility treatments are right for you.

If you decide to undergo IVF, compounded medicine can be used to induce and maintain pregnancy. For this type of treatment, doctors prescribe bioidentical hormones that match the molecular structure of the hormones found in your body. The prescription is customized by compounding pharmacies like Belmar Pharma Solutions, which offer personalized prescription solutions for hormonal health based on your unique body and needs. 

So, there you have it! 

Now that we’ve dropped some knowledge about menopause and IVF, you should feel more empowered to pursue fertility treatments. Most women don’t have major issues so don’t let fear stop you from going after what makes your life — and family — complete, a beautiful baby!


https://www.cdc.gov/art/whatis.html

https://www.tandfonline.com/doi/abs/10.3109/14647270903437923?journalCode=ihuf20

https://pubmed.ncbi.nlm.nih.gov/25398970/

https://www.researchgate.net/publication/354750116_Impact_of_IVF_on_the_Timing_and_Symptoms_of_Menopause

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6974869/

https://medlineplus.gov/ency/article/007279.htm

https://www.sciencedirect.com/science/article/abs/pii/S1472648310604725?via%3Dihub#

https://www.healthline.com/health/menopause/dealing-early

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2788687/

https://www.healthline.com/health/menopause/menopause-pregnancy#ivf

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3853428/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3181967/

Contact Belmar Pharma Solutions

Learn More

If you’re a patient, we’re here to help you fill prescriptions or provide you the information you need to work with your doctor to help decide if a compounded prescription might be a good treatment for you.

Prescribers, for a complete formulary or access to our clinical resources fill out the form below and one of our Solutions Engineers will be in touch shortly. If you are new to compounding, you may also find our page on How to Write a Compounding Prescription helpful.


    PatientPhysician
    Please choose one.




    State*




    Practice State*

    Please be advised: This form is not HIPAA compliant. Please do not provide information personal to your medical history or medication you currently take.

    By providing your email address you agree to receive promotional emails from Belmar Pharma Solutions.

    Thank you for reaching out. A member of our team is reviewing your message and will reach out as soon as possible. In the meantime, below are a few links, including our formulary, that we think you might find helpful:

    Formulary
    Conditions
    Patient Blog

    Thank you for reaching out. A member of our team is reviewing your message and will reach out as soon as possible. In the meantime, below are a few links, including our formulary, that we think you might find helpful:

    Formulary
    Treatment Options
    Clinician Blog
    Connect with Us!