The need for thyroid medication to optimize thyroid function is more common than one may realize. According to the American Thyroid Association, up to 60 percent of individuals with thyroid disease are unaware of their condition.

The thyroid is a small butterfly-shaped gland at the base of the neck that makes thyroid hormones triiodothyronine (T3) and thyroxine (T4). These hormones help the body use energy, stay warm, and keep organs functioning. When the thyroid doesn’t make as much thyroid hormone as the body needs, it is called hypothyroidism. Hypothyroidism is the most common reason for needing thyroid medicine, and can be caused by disease, surgery, radiation, or a pituitary gland that isn’t sending the thyroid the right signals.

While there is no cure for thyroid disease, Belmar Pharmacy can provide a range of compounded medications to help address these disorders.

thyroid medication image with smiling woman wearing glasses

Our Thyroid Medication Offerings

Liothyronine Sodium / Levothyroxine Sodium

Levothyroxine sodium is a synthetic bioidentical form of T4 that the body converts into active T3 as needed, while liothyronine sodium is a synthetic bioidentical form of T3 that provides the active thyroid hormone.

Levothyroxine Sodium

Levothyroxine is a synthetic version of the thyroid hormone T4 that converts into its active metabolite T3 (triiodothyronine).

Liothyronine Sodium

Liothyronine is a synthetic form of triiodothyronine (T3).

Desiccated Thyroid Compound

Desiccated thyroid is an extract derived from dried porcine thyroid glands that contains T3, T4, and additional triiodothyronine compounds.

About Thyroid Medications

thyroid medication image with woman cooking in kitchen

Diagnosis

Symptoms of thyroid disease may include a visibly enlarged thyroid gland in the neck, hair loss, and weight changes, since the thyroid plays an important role in regulating metabolism. Diagnosing thyroid problems typically involves evaluation of symptoms and a full thyroid panel blood test. Complete thyroid panels measure more than thyroid stimulating hormone (TSH) levels. They also include measuring free T3 and free T4 hormone levels.

To determine if someone has hypothyroidism (underactive thyroid), hyperthyroidism (overactive thyroid), or another problem, the provider will ask questions about health history and symptoms. In addition to blood tests, the provider may order imaging, such as an ultrasound. The results of these tests will determine the type of thyroid medication needed to restore thyroid function and hormones to optimal levels.

Benefits

Many people feel relief from symptoms of thyroid conditions with personalized thyroid hormone replacement therapy. For patients with hypothyroidism, signs that thyroid medication is working may include less fatigue and more energy, improved mood, and ability to lose weight more easily. Belmar Pharmacy compounds thyroid medications in a variety of dosage forms, allowing providers to adjust therapy for individual patient needs.

Long-term benefits of thyroid medications are designed to help people have a better quality of life, and also to help prevent the effects of an underactive or overactive thyroid on other systems in the body. Untreated thyroid conditions can contribute to serious health conditions, such as stroke, heart disease, infertility, and depression.

Considerations

Side effects of thyroid medication most commonly occur when a provider is trying to determine which dose and type of thyroid medication helps the patient feel their best. Compounded thyroid therapies may help minimize side effects since their strengths can be customized, the medication release modified, and  the inactive ingredients avoided to support sensitivities. Hypothyroidism patients adjusting to starting thyroid hormone replacement therapy may experience transient effects similar to having an overactive thyroid, which can include gastrointestinal issues, anxiety, weight loss, sleep disturbances, and high blood pressure. Side effects are typically short-lived once the medication is optimized for how the individual patient’s body responds.

Commonly Asked Questions About Thyroid Medications

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Belmar Pharmacy offers a variety of therapeutic options to support the body’s thyroid hormone balance. Compounded bioidentical forms of thyroid hormone replacement include synthetic T3/T4 options. Synthetic thyroid hormones are available as liothyronine sodium (T3) or levothyroxine sodium (T4). This form of thyroid hormone is biologically equivalent to the T3 and T4 in the human body, mimicking natural thyroid hormones. These active ingredients can also be compounded into combination oral formulations with both T3/T4.

The thyroid-stimulating hormone (TSH), is a hormone released by the pituitary gland. It tells the thyroid how much and when to release the hormones it produces called thyroxine (T4) and triiodothyronine (T3). If TSH doesn’t trigger the release of T3 and T4 from the thyroid gland, it can adversely affect metabolic, digestive, and heart functions.

There are many factors that can contribute to thyroid problems, including the pituitary gland’s ability to stimulate the thyroid to release its hormones into the body. The two most common thyroid problems are hypothyroidism (underactive thyroid) and hyperthyroidism (overactive thyroid). Several conditions can cause thyroid problems, including Hashimoto’s disease, a chronic autoimmune condition that can lead to an underactive thyroid.

Other conditions that may cause thyroid problems include iodine deficiency, Graves’ disease (the most common cause of hyperthyroidism), thyroid nodules, and thyroiditis.

Depending on whether a patient has hypothyroidism (underactive thyroid) or hyperthyroidism (overactive thyroid), they may experience opposite symptoms. If the thyroid is underactive, the patient may feel tired and cold, have a sluggish digestive system, feel depressed, and have trouble losing weight. When someone experiences hyperthyroid symptoms, they may feel anxious, lose weight quickly, have trouble sleeping, sweat easily, and have a faster heart rate. Either condition can cause an enlarged thyroid, or goiter, in the neck.

For women, hypothyroidism can mean heavier menstrual periods, and hyperthyroidism can contribute to irregular periods, or lack of them.

Depending on the type of thyroid medication taken, such as levothyroxine sodium, which is used to address hypothyroidism (underactive thyroid), too much thyroid medication may cause transient symptoms similar to those of hyperthyroidism (overactive thyroid). In this case, the patient may experience excessive sweating, rapid heartbeat, anxiety, diarrhea, weight loss, feeling jittery, shaking hands, and trouble sleeping.

Conversely, if the medication is addressing hyperthyroidism and the dose is too high, the patient may experience the opposite feelings of lethargy, lower heartbeat, feeling cold, depression, and mood swings.

Compounded thyroid replacement therapy allows for dose flexibility, combination therapy, and formulation adjustment. Liothyronine sodium (T3) and levothyroxine sodium (T4) can be combined into a single dosage form to improve ease of administration, and their strengths can be customized to meet individual patient needs. Compounded prescriptions can also be formulated to modify the release of the drug as well as to limit unnecessary fillers.

Proper thyroid function requires the conversion of T4, the primary inactive thyroid hormone, to T3, the body’s active thyroid hormone. Levothyroxine sodium (T4) has a naturally longer half-life. Liothyronine sodium (T3) has a shorter half-life, and patients in need of T3 support may benefit from a compounded modified release formulation. It is recommended to take thyroid hormone replacement therapy roughly 30 to 60 minutes before breakfast. Absorption tends to be higher on an empty stomach (at least 4 hours apart from food or supplements).

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