NAD+

What is NAD+?

NAD+ stands for Nicotinamide Adenine Dinucleotide, a coenzyme signaling molecule that is an essential part of the body’s cell makeup. Without it, basic biological processes would be at a standstill. Among its many functions, NAD+ is a necessary part of the biochemical reactions involved in metabolizing food for energy. NAD+ is also important for DNA repair which can ultimately affect overall health and longevity. 

Who May Benefit from NAD+ Therapy? 

  • Patients interested in experiencing potential increases in energy, endurance, mental clarity, and sleep quality may want to consider NAD+. Supplementing with NAD+ may help strengthen mitochondria, the powerhouses to the cell. Mitochondrial breakdown has been connected to age-related decline.  
  • As a coenzyme signaling molecule, NAD+ is a central player in cell function. NAD+ levels appear to decline with age, predominantly from the ages of 40 to 49. Low NAD+ levels may negatively affect important metabolic processes, such as sirtuin activity. Sirtuins are key proteins linked to aging, metabolism, and circadian rhythms.  
  • NAD+ dysregulation is often present in diseases related to oxidative stress or damage, such as conditions of the heart and brain. Studies investigating NAD+ support are promising, suggesting potential benefit for those with debilitating neurological disease states or metabolic issues. 

Available NAD+ Options 

NAD+ Subcutaneous Injectable
  • NAD+ is available as a 200 mg/mL sterile subcutaneous injection. 
  • Subcutaneous injections deliver medication into the fatty layer between skin and muscle for absorption into the bloodstream.  
  • Click here to learn more about how to perform a SC injection.
NAD+ Nasal Spray
  • NAD+ is available as a 300 mg/mL nasal spray.  
  • Nasal sprays deliver medication into the nasal mucosa for absorption into the bloodstream.

Who Should Avoid NAD+ Therapy? 

  • Patients with a sensitivity to niacin should seek medical advice before starting NAD+ therapy. Niacin, Vitamin B3, is a precursor to NAD+. In addition, patients with a history of liver disease or dysfunction may not be good candidates for NAD+ therapy and should consult with a healthcare provider.  
  • There may be other conditions that may affect your candidacy for compounded NAD+ medications. Please reach out to your medical provider for more clinical information and to discuss therapies appropriate for you.