Pregnenolone

What is Pregnenolone?

Pregnenolone is a steroid hormone synthesized from cholesterol in the adrenal glands and the central nervous system, serving as the essential precursor for all other steroid hormones. As a potent neurosteroid, it regulates neurotransmitter receptors and supports vital brain functions, including synaptic plasticity, myelination, and microtubule stabilization.

These actions are particularly significant in the hippocampus, where the hormone plays a key role in neuroprotection and the maintenance of cognitive health. Because natural levels typically decline after age 30, bioidentical compounded pregnenolone is often utilized to replicate these biological functions and support hormonal balance.